Article ID Journal Published Year Pages File Type
5848527 Chemico-Biological Interactions 2011 9 Pages PDF
Abstract
► V-PROLI/NO protects against the adverse effects of arsenic in rat liver cells. ► NO-releasing prodrug, V-PROLI/NO generates NO possibly via Cyp1a1 in rat liver cells. ► V-PROLI/NO reduces arsenic-induced toxicity and apoptosis. ► CYP450 required for NO production from V-PROLI/NO differs from rat and human.
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Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Preview
Nitric oxide donor, V-PROLI/NO, provides protection against arsenical induced toxicity in rat liver cells: Requirement for Cyp1a1
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