Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5849032 | Environmental Toxicology and Pharmacology | 2012 | 10 Pages |
Abstract
⺠We examined the chemopreventive effect of PFMet on 7,12-dimethylbenz(a)anthracene induced oral cancer. ⺠PFMet supplementation significantly restored the levels of TBARS and antioxidants status in pouch and plasma of tumor groups. ⺠The high dose of PFMet was more potent in inhibiting the oral cancer than the low dose and the medium dose. ⺠Our results signify that amla is a potential chemopreventive agent against oral carcinogenesis.
Keywords
GSHDuncan multiple range testDMBAGAETBARSGPXDMRTCAT7,12-dimethylbenz(a)anthraceneROSTAESODSuperoxide dismutasePhyllanthus emblicathiobarbituric acid reactive substancesbody weightLipid peroxidationCatalasehigh performance liquid chromatographyHPLCGlutathioneglutathione peroxidaseReactive oxygen species
Related Topics
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Health, Toxicology and Mutagenesis
Authors
Mani Krishnaveni, Sankaran Mirunalini,