Protective effect of lactofermented red beetroot juice against aberrant crypt foci formation, genotoxicity of fecal water and oxidative stress induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine in rats model

► We investigated the possibility detoxification of PHIP through diet. ► Dietary factor was the fermented red beet juice. ► Research was conducted in an animal model in rats. ► There was limitation of ACF changes in animals that fed fermented red beet juice. ► Showed reduced genotoxicity of intestinal contents in rats that fed fermented red beet juice. ► Reduced concentration of maloddialdehyde was found in the kidneys of rats fed with PhIP and fermented red beet juice. ► The presence of fermented red beet juice in the diet of rats increased the count of bacteria including Lactobacillus/Enterococcus and Bacterides-Prevotella group adhered to colonic epithelium.