| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5855143 | NeuroToxicology | 2013 | 10 Pages |
Abstract
⺠Mn3+ can be transported into neuronal cells via the Tf mechanism. ⺠This transport shows characteristics similar to those of Fe3+ transport via this same mechanism. ⺠The amount of this transport in the neuronal cells used was much less than transport of the same concentration of Mn2+. ⺠Because Mn3+ is a strong oxidizing agent, it is transport via the Tf mechanism, could also cause oxidative damage to endosomes.
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Authors
Thomas E. Gunter, Brent Gerstner, Karlene K. Gunter, Jon Malecki, Robert Gelein, William M. Valentine, Michael Aschner, David I. Yule,