| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5855199 | NeuroToxicology | 2012 | 16 Pages |
Abstract
⺠Behavior studies revealed that the mice exposed to Pb during development were less prone to explore and had memory impairment. ⺠As adults the Pb exposed males displayed aggressive behavior towards their cage-mates, but ignored a stranger intruder. ⺠Microarray analysis of brain RNA at pnd21 indicated Pb was affecting pathways important for neuronal development. ⺠Brain gene expression analysis at pnd21 indicated inflammation in the brain. ⺠Vomeronasal receptor gene expression, associated with regulation of social behaviors, was altered by Pb in the brain at pnd21.
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Jane Kasten-Jolly, Nina Pabello, Valerie J. Bolivar, David A. Lawrence,