Exposure of young rats to diphenyl ditelluride during lactation affects the homeostasis of the cytoskeleton in neural cells from striatum and cerebellum

► Dam exposure to low doses of diphenyl ditelluride causes neurotoxicity in their offspring. ► Diphenyl ditelluride via maternal milk targets phosphorylating/dephosphorylating pathways in striatum and cerebellum of pups. ► Diphenyl ditelluride disrupts cerebellary and striatal cytoskeleton of suckling pups exposed via milk. ► Diphenyl ditelluride alters cellular signaling targeting the cytoskeleton of neural cells of pups via maternal milk. ► Diphenyl diselenide partially prevented the neurotoxic effects of diphenyl ditelluride.