Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5855257 | NeuroToxicology | 2012 | 9 Pages |
Abstract
⺠Chick embryonic neurodevelopmental deformity occurred following 2,5-HD exposure. ⺠2,5-HD exposure resulted in neural tube defect (NTD) in developing chick embryo. ⺠In addition to NTD, the neurofilament-marked neuron differentiation was impaired. ⺠The neurite development in primary neuron culture in vitro was inhibited as well. ⺠2,5-HD exposure abridged chick embryonic neuron's viability in MTT and MPP assays.
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Authors
Xin Cheng, Guang Wang, Zheng-lai Ma, Yun-yu Chen, Jing-jing Fan, Zhao-long Zhang, Kenneth Ka Ho Lee, Huan-min Luo, Xuesong Yang,