| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5855293 | NeuroToxicology | 2012 | 9 Pages |
Abstract
⺠Mutations at V787 in rat Nav1.4 channels modulate slow inactivation gating. ⺠V787 mutations modulate SCI insecticide inhibition independent of changes in gating. ⺠Effects of V787 mutations on SCI insecticide inhibition are compound specific. ⺠Effects of V787 mutations on metaflumizone correlate with substituent hydrophobicity. ⺠V787 may be a unique determinant of metaflumizone binding.
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Authors
Richard T. von Stein, David M. Soderlund,