| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5855351 | NeuroToxicology | 2012 | 6 Pages |
Abstract
⺠We examined the role of glutathione and oxidative stress in methylmercury toxicity. ⺠A temporal burst of reactive oxygen species was cytoprotective. ⺠Methylmercury depleted glutathione likely via conjugation. ⺠The conjugate is exported by MRP-1 and sensitive to blockade by MK-571. ⺠Export of the conjugate is required for glutathione mediated protection.
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Authors
Travis Rush, XiaoQian Liu, Andrew B. Nowakowski, David H. Petering, Doug Lobner,