| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5855358 | NeuroToxicology | 2012 | 9 Pages |
Abstract
⺠Rutin inhibits Aβ42 fibrillization and attenuates Aβ42-induced cytotoxicity. ⺠Rutin decreases the formation of active oxygen species (ROS). ⺠Rutin decreases the formation of glutathione disulfide (GSSG) and malondialdehyde (MDA). ⺠Rutin decreases the production of TNF-α, and IL-1β.
Keywords
MDA2′,7′-dichlorfluorescein-diacetateIL-6IL-1βDCFH-DAiNOSGSSGGPXAβGSHCAT3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromideMTTROSβ-AmyloidTeminterleukin1βinterleukin-6ThTAlzheimer's diseaseAggregationtumor necrosis factor alphaThioflavin TSODinducible nitric oxide synthaseSuper Oxide Dismutaseproinflammatory cytokinesTNF-αmalondialdehydeRutinTransmission electron microscopeNitric oxideβ-amyloid peptideCatalaseGlutathioneglutathione disulfideglutathione peroxidaseReactive oxygen species
Related Topics
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Authors
Shao-wei Wang, Yu-Jiong Wang, Ya-jing Su, Wei-wei Zhou, Shi-gao Yang, Ran Zhang, Min Zhao, Ya-nan Li, Zi-ping Zhang, Da-wei Zhan, Rui-tian Liu,