| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5855470 | NeuroToxicology | 2011 | 9 Pages |
Abstract
⺠We examine effects of LPS on airway neural mechanisms associated with inflammation. ⺠LPS increases innervation of airway sensory C-fibers in preweaning rats. ⺠LPS increases tachykinin NK1 receptors in the airways of preweaning rats. ⺠LPS causes overproduction of neurotrophins, mainly through a TNF-α-mediated pathway. ⺠LPS results in enhancement of neurogenic airway inflammation in preweaning rats.
Keywords
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Authors
Masanori Takeda, Mio Miyake, Taichiro Muto, Michihiro Kamijima, Tatsuo Sakamoto,