Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5856440 | Regulatory Toxicology and Pharmacology | 2014 | 15 Pages |
Abstract
The results of this exercise represent preliminary categorisations and must not be used as a basis for definitive regulatory decisions. They demonstrate that a combination of criteria for hazard identification with additional criteria of hazard characterisation allows prioritising and differentiating between substances with regard to their regulatory concern. It is proposed to integrate these elements into a decision matrix to be used within a weight of evidence approach for the toxicological categorisation of relevant endocrine disruptors and to consider all parts of the endocrine system for regulatory decision making on endocrine disruption.
Keywords
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Authors
P. Marx-Stoelting, L. Niemann, V. Ritz, B. Ulbrich, A. Gall, K.I. Hirsch-Ernst, R. Pfeil, R. Solecki,