Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5856594 | Regulatory Toxicology and Pharmacology | 2015 | 9 Pages |
Abstract
The concentrations of metals (Cd, Pb, Ni, Cr, Cu, Co, Fe, Mn, Zn and Al) were determined in thirty brands of popular of underarm cosmetics in Nigeria with a view to providing information on the levels of metals and the risk of exposure to metals by humans through long time usage of these products. The concentrations of metals in these samples of underarm cosmetics were measured by using atomic absorption spectrometry after acid digestion. The concentrations of metals in these types of underarm cosmetics studied ranged from <0.15 to 1.2 μg gâ1 Cd, <0.02 to 11.2 μg gâ1 Pb, <0.03 to 4.9 μg gâ1 Ni, <0.1 to 25.0 μg gâ1, <0.02 to 2.8 μg gâ1 Co, 2.0 to 6.4 μg gâ1 Cu, 4.7 to 91.2 μg gâ1 Fe, <0.05 to 14.1 μg gâ1 Mn, 77.9 to 132 μg gâ1 and 69.2 to 83,500 μg gâ1 Al. The results of this study indicate that Cd, Pb, Ni, Cr and Co were presents in these types of underarm cosmetics at concentrations below the regulatory control limits for metal impurities in color additives for cosmetics and suggested limits following good manufacturing practice. The estimated margin of safety (MoS) indicated that the concentrations of the examined metals in these underarm cosmetic products present no potential risk to the users. The continuous use of these brands of underarm cosmetics represents a potential source of human exposure to metals such as aluminum in the local area of the breast, particularly to the upper outer quadrant.
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Authors
Chukwujindu M.A. Iwegbue,