Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5856783 | Regulatory Toxicology and Pharmacology | 2014 | 6 Pages |
Abstract
- Cholinesterase was inhibited in humanized mice with liver after oral acephate.
- Plasma acephate and chlorpyrifos in humanized mice supported human concentrations.
- Chimeric mice with a PBPK can evaluate potential of organophosphorus pesticides.
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Authors
Hiroshi Suemizu, Shigeto Sota, Miyuki Kuronuma, Makiko Shimizu, Hiroshi Yamazaki,