| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5856959 | Regulatory Toxicology and Pharmacology | 2013 | 11 Pages |
Abstract
⺠The safety of a glucose oxidase preparation derived from Penicillium chrysogenum (PGO) was investigated. ⺠No adverse effects were observed at doses of up to 15,600 U/kg body weight/day in rats in a 90-day study. ⺠PGO was non-genotoxic in a series of genotoxicity tests. ⺠The results of these studies support the safe use of PGO in food processing.
Keywords
GLP2-aminoanthraceneOECDMCHALTAF-2MCHCMCVAPTTNaOHHCl9-AANaN32-(2-furyl)-3-(5-nitro-2-furyl)acrylamideEDTA-2K2-AAA/GDNAγ-glutamyl transpeptidaseHydrogen peroxideASTAspartate aminotransferaseAlanine aminotransferaseALPAlkaline phosphatasedeoxyribonucleic acidGood Laboratory PracticeMean corpuscular volumeBUNactivated partial thromboplastin timesodium azideSodium hydroxide, Caustic Sodamitotic indexmean corpuscular hemoglobinMean corpuscular hemoglobin concentrationblood urea nitrogenH2O2body weightHydrogen chloride
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Authors
Tetsuya Konishi, Takuya Aoshima, Fukutaro Mizuhashi, Sharon S.H. Choi, Ashley Roberts,