Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5856966 | Regulatory Toxicology and Pharmacology | 2013 | 6 Pages |
Abstract
⺠Performance of the reduced LLNA was assessed using REACH registrations. ⺠The reduced LLNA misclassified 3.3% of the sensitizers identified in the LLNA. ⺠The reduced LLNA is less accurate than the LLNA. ⺠The reduced LLNA does not provide potency information. ⺠We do not recommend the use of the reduced LLNA as a standalone method for skin sensitization testing.
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Authors
Janine Ezendam, Andre Muller, Betty C. Hakkert, Henk van Loveren,