Reduced exposure evaluation of an Electrically Heated Cigarette Smoking System. Part 3: Eight-day randomized clinical trial in the UK

► Electrically heated cigarette smoking systems compared to conventional cigarettes. ► Mainstream smoke constituents reduced in electrically heated cigarettes. ► Biomarkers of exposure confirmed reduced exposure in a randomized clinical trial. ► Reductions in exposure to selected smoke constituents approach smoking cessation. ► No clinically relevant adverse effects observed.