| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5857099 | Regulatory Toxicology and Pharmacology | 2013 | 5 Pages |
Abstract
⺠Tobacco smoke particulate matter (PM) was stored at â80 °C for up to 2 years. ⺠Fresh and stored PMs were compared in the Ames test, MLA, MNvit and NRU assays. ⺠Majority of comparisons demonstrated no differences between fresh and stored PM. ⺠Where differences were observed they showed no consistent trends or patterns. ⺠The minor differences were not attributed to a specific storage related effect.
Keywords
ICCVAMIC50ANCOVAGVPBATMLAMnBnCOMGLPDMSOMouse lymphoma assayISOanalysis of covarianceGood Laboratory PracticeBritish American TobaccoDimethyl sulfoxideMutant frequencyCooperation Centre for Scientific Research Relative to TobaccoICHInteragency Coordinating Committee on the Validation of Alternative MethodsInternational Conference on HarmonisationCORESTA
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Authors
I. Crooks, D.M. Dillon, J.K. Scott, M. Ballantyne, C. Meredith,