Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5857136 | Regulatory Toxicology and Pharmacology | 2012 | 9 Pages |
Abstract
⺠Mice were exposed to 182 mg/L Cr(VI) in drinking water for 7 days. ⺠Duodenal epithelial cells were collected and analyzed by whole genome microarray. ⺠Gene changes were compared between Cr(VI) and eight mutagens and nonmutagens. ⺠A logistic regression classification model was built for eight mutagens and nonmutagens. ⺠Mutagens and nonmutagens formed two clusters; Cr(VI) clustered with nonmutagens.
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Authors
Chad M. Thompson, J. Gregory Hixon, Deborah M. Proctor, Laurie C. Haws, Mina Suh, Jonathan D. Urban, Mark A. Harris,