Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5857277 | Regulatory Toxicology and Pharmacology | 2012 | 10 Pages |
Abstract
⺠Conducted a preliminary quality control (QC) evaluation of the 96 h LC50 testing protocol. ⺠Eight percent of data failed key assumption validation, no steady-state LC50s could be estimated. ⺠Remaining data contained unquantified variance from toxicity modifying factors. ⺠A formal QC evaluation is warranted as results are not comparable measures of relative toxicity. ⺠Interim improvements in design, execution, and interpretation of LC50 tests are needed.
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Authors
L.S. McCarty,