| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5857379 | Regulatory Toxicology and Pharmacology | 2011 | 10 Pages |
Abstract
⺠Toxic liver injury by the herb Greater Celandine (GC) created regulatory concern in Europe. ⺠In Germany, 22 spontaneous cases of assumed GC hepatotoxicity have been presented. ⺠Regulatory causality for GC was probable in 16 and possible in 6 cases. ⺠With a liver specific method, causality was now probable or higher in 8 cases. ⺠Regulators should use a liver specific rather than unspecific causality assessment method.
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Authors
Rolf Teschke, Xaver Glass, Johannes Schulze,