| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5857380 | Regulatory Toxicology and Pharmacology | 2011 | 4 Pages |
Abstract
⺠Heat stability of biotech proteins is part of the weight of evidence for potential allergenicity. ⺠Heat stability is evaluated by monitoring loss of functional activity at various temperatures. ⺠The temperatures that are selected reflect normal processing conditions of that crop. ⺠Applying immunodetection methods in this evaluation does not inform the safety assessment.
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Authors
Laura Privalle, Gary Bannon, Rod Herman, Gregory Ladics, Scott McCLain, Nicola Stagg, Jason Ward, Corinne Herouet-Guicheney,