Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5857521 | Regulatory Toxicology and Pharmacology | 2011 | 13 Pages |
Abstract
⺠Toxicogenomic technologies will become important for regulatory decisions in the future. ⺠There is concern with premature use and over-interpretation of this technology. ⺠Clear guidance on data interpretation is needed prior to use in regulatory decisions. ⺠Agencies need to continue developing use of computational and molecular technologies.
Keywords
Comparative Toxicogenomics DatabaseRfDRFCMOAPPARαMAQCBMDdibutyl phthalateCTDRT-PCRMicroArray Quality ControlWOEFDALO(A)ELNO(A)ELDBPNRCPODMinimum Information About a Microarray ExperimentEPACFSANOPPperoxisome proliferator-activated receptor alphaEnvironmental Protection AgencyRisk assessmentESTGene expressionMode of actionKEGG یا Kyoto Encyclopedia of Genes and Genomes Kyoto Encyclopedia of Genes and GenomesReference dosebenchmark doseMicroarrayFood and Drug AdministrationCancerToxicogenomicsNational Research CouncilReference concentrationCARMIAMEPoint of departureGene ontologyno observed (adverse) effect levelORDReal time polymerase chain reactionWeight of evidence
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Amber K. Goetz, Bhanu P. Singh, Michael Battalora, Joseph M. Breier, Jason P. Bailey, Amechi C. Chukwudebe, Erik R. Janus,