| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5857536 | Regulatory Toxicology and Pharmacology | 2011 | 10 Pages |
Abstract
⺠The impact of second generation effects on classification and labelling was analysed. ⺠The second generation was not decisive for 50 classified substances except fenarimol. ⺠Fenarimol provided endocrine and developmental neurotoxicity alerts. ⺠In the EOGRTS fenarimol would thus be detected as a developmental neurotoxicant. ⺠These results support replacement of the 2-generation reprotox study by the EOGRTS.
Keywords
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Authors
Emiel Rorije, André Muller, Manon E.W. Beekhuijzen, Ulla Hass, Barbara Heinrich-Hirsch, Martin Paparella, Erna Schenk, Beate Ulbrich, Betty C. Hakkert, Aldert H. Piersma,