| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5857574 | Regulatory Toxicology and Pharmacology | 2012 | 10 Pages |
Abstract
⺠The subchronic toxicity of the total flavonoids (TFs) from Rosa laevigata Michx fruit was tested. ⺠The TFs was oral administered to rats at the doses of 500, 1000 and 2000 mg/kg/day. ⺠The doses of 1000 and 500 mg/kg/day for male and female rats were selected as the NOAEL. ⺠The study provides useful data for new drug exploration of the TFs from R. laevigata Michx fruit.
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Authors
Shuai Zhang, Lingli Zheng, Lina Xu, Huijun Sun, Hua Li, Jihong Yao, Kexin Liu, Jinyong Peng,