| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5857575 | Regulatory Toxicology and Pharmacology | 2012 | 10 Pages |
Abstract
⺠We developed a decision tree for Exposure Based Waiving in REACH for human health. ⺠The tree uses fixed criteria and illustrative guidance to guide the user. ⺠For quantitative assessment (draft) Thresholds of Toxicological Concern are used. ⺠The tool is built into a webtool on integrated testing strategies.
Keywords
MMADITSEBWADMETTCPROCDNELEBTIntegrated testing strategiesIntegrated testing strategyOsirisRegistration, Evaluation, Authorisation and Restriction of Chemicalsabsorption, distribution, metabolism, excretionREACHDerived No Effect LevelMass median aerodynamic diameterConsumersMolecular weightWorkersKow
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Authors
Hans Marquart, Tim Meijster, Marja Van de Bovenkamp, Wouter Ter Burg, Suzanne Spaan, Jacqueline Van Engelen,