Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5857576 | Regulatory Toxicology and Pharmacology | 2012 | 7 Pages |
Abstract
⺠We discuss the value of toxicokinetics in toxicology study design and dose selection. ⺠In-house and literature examples of chemical/agrochemical data are presented. ⺠Toxicokinetics helps ensure studies are of most relevance for risk assessment. ⺠And helps avoid excessively high doses and unnecessary animal suffering.
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Authors
Stuart Creton, Shakil A. Saghir, Michael J. Bartels, Richard Billington, James S. Bus, Will Davies, Matthew P. Dent, Gabrielle M. Hawksworth, Simon Parry, Kim Z. Travis,