Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5857582 | Regulatory Toxicology and Pharmacology | 2012 | 14 Pages |
Abstract
⺠We evaluated the weight of evidence for methanol carcinogenesis in humans. ⺠Our Hypothesis-Based Weight-of-Evidence approach is applied to study quality issues. ⺠Bioassays and mode of action were interpreted with a hypothesis-based approach. ⺠We weighed consistency and plausibility of inferential logic about human risk. ⺠We considered alternative explanations for outcomes of questioned studies.
Keywords
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Authors
Lisa A. Bailey, Robyn L. Prueitt, Lorenz R. Rhomberg,