| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5857680 | Regulatory Toxicology and Pharmacology | 2013 | 11 Pages |
Abstract
⺠Pharmacokinetics of metoprolol and telmisartan as singly/combination in rat. ⺠Pharmacodynamics of metoprolol and telmisartan as singly/combination in rat. ⺠Subchronic toxicity of metoprolol and telmisartan as singly/combination in rat.
Keywords
CmaxTELAUC0–∞SGPTAUC0–tSGOTIAECCPCSEAMCHCPLTMCHtmaxRBCHCTWBCLC–MS/MSt1/2ALPAlkaline phosphataseinternal standardTelmisartanmaximum plasma concentrationBUNReticulocytestime to reach Cmaxserum glutamate oxaloacetate transaminasePharmacokineticssystolic blood pressureAntihypertensive activitymean corpuscular hemoglobinMetoprolol succinateToxicity studyMETMean corpuscular hemoglobin concentrationblood urea nitrogenhematocritHemoglobinPlateletKeltotal proteininstitutional animal ethics committeeCommittee for the Purpose of Control and Supervision of Experiments on Animalswhite blood cellred blood cellserum glutamate pyruvate transaminase
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Authors
Utpal Nandi, Sanmoy Karmakar, Anjan Kumar Das, Balaram Ghosh, Aswathi Padman, Nilendra Chatterjee, Tapan Kumar Pal,