Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5857754 | Regulatory Toxicology and Pharmacology | 2012 | 7 Pages |
Abstract
⺠Lymph node angiomas range from rare to common in 2-year carcinogenicity studies. ⺠Lymph node angiomas are most common in male rats in 2-year carcinogenicity studies. ⺠Drug-induced mesenteric lymph node angiomas in rats can be up to 40% in male rats. ⺠Lymph node angiomas in rats are not precursors of lymph node angiosarcomas. ⺠Lymph node angiomas in rats are not relevant to human risk assessment.
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Authors
Zaher A. Radi, Daniel Morton,