Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5858098 | Reproductive Toxicology | 2016 | 7 Pages |
â¢Levels of 9 PFCs in cord serum samples were measured by HPLC/MS/MS.â¢The effects of PFASs on birth weight were examined using regression analysis.â¢The none of PFASs was statistically associated with birth weight in this population.
The effects of exposure to the perfluoroalkyl and polyfluoroalkyl substances (PFASs) perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) on birth weight have been examined in several studies, but other PFASs have not been considered. We conducted a cross-sectional survey of newborns in Seoul, South Korea, collecting 118 serum samples, for 85 of which we had a full range of information. We conducted multiple regression analyses to examine the association between nine PFAS concentrations in cord serum and birth weight. Seven PFASs were found in cord serum, PFOA and PFOS being dominant, with mean concentrations of 1.11 and 0.87Â ng/mL, respectively. The adjusted birth weight changes (natural log) were â0.14 (95% confidence interval â0.33-0.03) for PFOS and â0.03 (95% confidence interval â0.25-0.18) for PFOA. None of the PFASs were statistically associated with birth weight in this population.