The potential of AOP networks for reproductive and developmental toxicity assay development

- The AOP framework forms a basis for the development of non-animal test methods.
- AOP networks often more realistically represent potential chemical effects.
- AOP networks can improve assay development by increasing confidence in results.
- AOP networks allow selection of assay specificity relative to the mode of action.
- AOP networks can aid in prioritization and application of new assays.