Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5859170 | Toxicology | 2015 | 11 Pages |
Abstract
Overall, long-term BPA exposure induces cardiomyopathy in male rats, and the underling mechanism may involve the impairment of cardiac mitochondrial function and the disturbance of methylation of PGC-1α.
Keywords
PGC-1αDNMT3ANRF-2DNA methyltransferase 3BDNMT3BDnmt1DNA methyltransferase 3aBPATFAMNRF-1CpGPPARαMRCPPARγtranscription factor A, mitochondrialcytosine phosphate guanineMMPUQCRC2peroxisome proliferator-activated receptor alphaMitochondrial dysfunctionBisphenol ANuclear respiratory factor 1nuclear respiratory factor 2DNA methylationMitochondrial membrane potentialCardiomyopathyPeroxisome proliferator-activated receptor gamma
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Authors
Ying Jiang, Wei Xia, Jie Yang, Yingshuang Zhu, Huailong Chang, Juan Liu, Wenqian Huo, Bing Xu, Xi Chen, Yuanyuan Li, Shunqing Xu,