Article ID Journal Published Year Pages File Type
5859385 Toxicology 2013 8 Pages PDF
Abstract
► Cathepsins B and D were markedly enhanced by octylphenol (OP) in MCF-7 cells. ► OP may accelerate breast cancer cell growth and cathepsins via ER-mediated signaling. ► Breast cancer cells exposed with OP to mouse model were more aggressive. ► OP can promote metastasis through the amplification of cathepsins B and D via ER-mediated signaling pathway.
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
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