| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5859402 | Toxicology | 2013 | 8 Pages |
Abstract
⺠OTA raised Spiâ mutant frequency in the kidneys of p53-deficient gpt delta mice. ⺠OTA induced significant increase of p53 protein levels in the kidneys of mice. ⺠A lack of p53 elevated incidences of apoptosis and karyomegaly in renal tubules. ⺠OTA-induced phenomenon may arise from DNA damage.
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Authors
Daisuke Hibi, Aki Kijima, Yuta Suzuki, Yuji Ishii, Meilan Jin, Yoshiko Sugita-Konishi, Tokuma Yanai, Akiyoshi Nishikawa, Takashi Umemura,