Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5859650 | Toxicology | 2011 | 9 Pages |
Abstract
⺠The study examines pulmonary response in mice exposed to BaP by oral gavage. ⺠We examined pulmonary gene and miRNA expression changes and measured DNA adducts. ⺠We compare the mechanisms of action that operate in lungs relative to the liver. ⺠We show differences in biological pathways activated in lungs versus the liver. ⺠We suggest that liver miRNAs are less sensitive to perturbations than lung miRNAs.
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Authors
Sabina Halappanavar, Dongmei Wu, Andrew Williams, Byron Kuo, Roger W. Godschalk, Frederik J. Van Schooten, Carole Lyn Yauk,