| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5859663 | Toxicology | 2011 | 8 Pages |
Abstract
⺠Delayed rectifier K+ current in Jurkat T lymphocytes was characterized. ⺠Aconitine-induced block of this current was examined. ⺠The IC50 value for aconitine-induced inhibition of IMEP was 5.6 μM. ⺠Aconitine inhibited this current in a concentration- and state-dependent manner.
Keywords
FBSDelayed-rectifier K+ current1-ethyl-2-benzimidazolinoneIKCa channel1-EBIOIK(DR)ACOMgTxIC50SSRI–VK+ currentAconitinecurrent–voltageDissociation constantstandard error of meanfetal bovine serumInactivation kineticsLymphocytemargatoxinsum of squared residualsSEMVoltage-dependent K+ channelKv channel
Related Topics
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Authors
Sheng-Nan Wu, Bing-Shuo Chen, Yi-Ching Lo,