Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5860341 | Toxicology Letters | 2014 | 7 Pages |
Abstract
- Hypoxia or CoCl2 treatment induced hepatic intracellular fat accumulation.
- Hypoxia or CoCl2 treatment impaired fatty acid β-oxidation mediated by PGC-α.
- Both HIF-1α and HIF-2α are critically involved in hypoxia-induced lipid accumulation in hepatocytes.
Keywords
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Authors
Yanlong Liu, Zhenhua Ma, Cuiqing Zhao, Yuhua Wang, Guicheng Wu, Jian Xiao, Craig J. McClain, Xiaokun Li, Wenke Feng,