Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5860379 | Toxicology Letters | 2014 | 6 Pages |
Abstract
- This study was to establish a method to analyze estrogen quinone-derived adducts.
- These adducts were measured in hemoglobin derived from breast cancer patients.
- A 6-fold increase in mean values of adducts in breast cancer patients was detected.
- Estrogen quinone hemoglobin adducts is an important indicator of breast cancer risk.
Keywords
NACCYP1B1N-acetyl-l-cysteineCYP1A1TFAMSAALBNCItrifluoroacetic acid anhydrideTFAA17β-estradiolGC–MSTrifluoroacetylAlbuminMethanesulfonic acidstandard deviationElectron impactcytochrome P450 1A1cytochrome P450 1B1BiomarkersHemoglobinProtein adductshigh performance liquid chromatographyHPLCQuinonesNegative ion chemical ionization
Related Topics
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Environmental Science
Health, Toxicology and Mutagenesis
Authors
Che Lin, Wei-Chung Hsieh, Dar-Ren Chen, Shou-Jen Kuo, Wen-Fa Yu, Suh-Woan Hu, Hung-Jie Sue, Mao-Hui Ko, Chang-Hsin Juan, Kuo-Suan Chung, Po-Hsiung Lin,