| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5860383 | Toxicology Letters | 2014 | 9 Pages |
Abstract
- We used Caenorhabditis elegans to investigate how TBTCL exhibits its effect on animal germline.
- TBTCL exposure resulted in increased sterility and embryonic lethality.
- TBTCL exposure induced increased DSBs and checkpoint activation in germline.
- Germ cell apoptosis and proliferation arrest were induced by TBTCL exposure.
- Checkpoint and p53 signaling pathways were found essential in response to TBTCL.
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Authors
Zhe Cheng, Huimin Tian, Hongran Chu, Jianjian Wu, Yingying Li, Yanhai Wang,