Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5860554 | Toxicology Letters | 2013 | 12 Pages |
Abstract
- Wogonin inhibited C6 cells growth and arrested at G0/G1 phase of the cell cycle.
- Wogonin induced typical morphological changes and an increase in GFAP level.
- Induction of cell differentiation by wogonin ascribed to the restrain of GSK-3β/β-catenin pathway.
- Blocking GSK-3β/β-catenin signaling promotes the glial differentiation of glioma cells.
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Authors
Yajing Wang, Yi Zhang, Chen Qian, Min Cai, Yan Li, Zhiyu Li, Qidong You, Qing Wang, Rong Hu, Qinglong Guo,