Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5860566 | Toxicology Letters | 2013 | 11 Pages |
Abstract
⺠PM2.5 alone caused injuries in heart and systemic function of rats. ⺠Ozone alone did not induce similar adverse effects, but enhanced PM2.5 toxicology. ⺠A dose-depend relationship was observed in ozone plus PM2.5 exposure. ⺠Dysfunction of ANS might be one of the biological mechanisms of PM2.5.
Keywords
VPBsIL-6Concentrated ambient particlesMDAAutonomic nervous system (ANS)Residual Oil Fly AshCAPSET-1SBPPM2.5HRVinflammationelectrocardiogramECGendothelin-1OzoneTeminterleukin-6Oxidative stressTotal variationAutonomic nervous systemFine particulate matter (PM2.5)Fine particulate mattersANSSODROFASuper Oxide DismutaseVentricular premature beatsHeart rateVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)systolic blood pressurehigh-frequency powerlow-frequency powerHeartlactate dehydrogenaseLDHmalondialdehydeTransmission electron microscopyheart rate variabilityC-reactive proteinCRPCreatine kinaseCarbon black
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Authors
Guanghe Wang, Rongfang Jiang, Zhuohui Zhao, Weimin Song,