Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5860651 | Toxicology Letters | 2012 | 10 Pages |
Abstract
⺠Thymic Treg cells are preserved from reducing effects of AhR on precursor T cells. ⺠AhR activation does not increase the number of CD4+CD25+Foxp3+ Treg cells in the thymus and MLN, but increases the number of these Treg cells in the spleen. ⺠AhR activation decreases the number of precursor and effector T cells. ⺠Effects of AhR activation on T cells are partly independent of sensitization.
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Authors
V.J. Schulz, J.J. Smit, M. Bol-Schoenmakers, M.B.M. van Duursen, M. van den Berg, R.H.H. Pieters,