Article ID Journal Published Year Pages File Type
5860677 Toxicology Letters 2012 8 Pages PDF
Abstract
► TOCP could disrupt the seminiferous epithelium and decrease the sperm density in the mouse testis. ► NTE was shown to exist in spermatogonial stem cells and to be inhibited by TOCP. ► SCOTP inhibited NTE activity in spermatogonial stem cells. ► Both inhibition and knockdown of NTE activity inhibited cell proliferation.
Keywords
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
Preview
Involvement of neuropathy target esterase in tri-ortho-cresyl phosphate-induced testicular spermatogenesis failure and growth inhibition of spermatogonial stem cells in mice
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