| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5860685 | Toxicology Letters | 2012 | 7 Pages |
Abstract
⺠N7-(3-benzo[1,3]dioxol-5-yl-2-hydroxypropyl)guanine (N7γ-SFO-Gua) was characterized. ⺠An HPLC-ESI-MS/MS method was first developed to measure N7γ-SFO-Gua. ⺠N7γ-SFO-Gua was detected in urine of mice treated with safrole 2â²,3â²-oxide (SFO). ⺠This is the first study to suggest the formation of N7γ-SFO-Gua in SFO-treated mice.
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Authors
Li-Ching Shen, Su-Yin Chiang, Ming-Huan Lin, Wen-Sheng Chung, Kuen-Yuh Wu,