Article ID Journal Published Year Pages File Type
5860694 Toxicology Letters 2012 7 Pages PDF
Abstract
► Myelin basic protein (Mbp) gene produces alternate transcripts by splicing. ► We identified a new Mbp splice variant in rat expressed in developing brain. ► We developed a PCR-based approach to properly measure all Mbp splice variants. ► As expected, perinatal exposure to methylmercury decreased Mbp gene expression. ► Methylmercury did not impact the relative expression of Mbp splice variants.
Related Topics
Life Sciences Environmental Science Health, Toxicology and Mutagenesis
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