| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5860703 | Toxicology Letters | 2012 | 8 Pages |
Abstract
⺠Cadmium causes a necrotic cell death in endothelial cells. ⺠Cd-induced necrosis is a programmed, BCL-XL-inhibitable process. ⺠Lysosomal membrane permeabilization and release of DNAse II are central in the execution of cell death. ⺠DNAse-mediated degradation of nuclear DNA results in “apoptosis mimicry” in several cell death assays.
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Barbara Messner, Christian Ploner, Günther Laufer, David Bernhard,