Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5860716 | Toxicology Letters | 2011 | 6 Pages |
Abstract
⺠In this study, we constructed a cDNA T7 phage display library from sea snake. ⺠Many reported and unreported sea snake venom proteins were identified. ⺠Four different short chain neurotoxins (SNT-1, 2, 3, 4) were cloned and expressed. ⺠SNT-4 was a new neurotoxin and showed potential as pain killer. ⺠The interaction mode between SNTs and nAChR was simulated through computer modeling.
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Authors
Taochao Tan, Xi Xiang, Hong Qu, Shenggeng Zhu, Qun Bi,