Up-regulation of cyclin D1 by JNK1/c-Jun is involved in tumorigenesis of human embryo lung fibroblast cells induced by a low concentration of arsenite

Article ID	Journal	Published Year	Pages	File Type
5860795	Toxicology Letters	2011	8 Pages	PDF

Abstract

âº Neoplastic transformation induced by a low level of arsenite. âº Cell proliferation and cell cycle regulation induced by a low level of arsenite. âº JNK1/c-Jun/cyclinD1 signal pathways.

Keywords

NF-κB CDK Cyclin D1 JNKs MAPKs Mitogen activated protein kinases arsenite Neoplastic transformation c-Jun retinoblastoma nuclear factor kappa B Phosphoinositide 3-kinases Cell cycle HELF cyclin-dependent kinase

Related Topics

Life Sciences Environmental Science Health, Toxicology and Mutagenesis

Preview

Up-regulation of cyclin D1 by JNK1/c-Jun is involved in tumorigenesis of human embryo lung fibroblast cells induced by a low concentration of arsenite

Authors

Yuan Li, Lu Shen, Hui Xu, Ying Pang, Yuan Xu, Min Ling, Jianwei Zhou, Xinru Wang, Qizhan Liu,