| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5860826 | Toxicology Letters | 2011 | 7 Pages |
Abstract
⺠Dioxins impacted Leydig cells through regulation of AhR, AhRR and Cyp1b1. ⺠Ccl5 and Cxcl4 were 2 chemokines regulated by TCDD in Leydig cells. ⺠The steroidogenic outcome of Leydig cells was not targeted by TCDD. ⺠TCDD effect on AhRR was opposed by the trophic hormone (hCG). ⺠TNFα stimulated AhR gene expression and did not oppose TCDD effect on AhRR.
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Authors
Danielle Naville, Diane Rebourcet, Marie-Agnès Chauvin, Nathalie Vega, Audrey Jalabert, Michèle Vigier, Emmanuelle Loizon, Martine Bégeot, Brigitte Le Magueresse-Battistoni,